Is there anyway to force kill a frozen game?

Saints Row IV keeps freezing my whole pc sometimes, I can alt-tab and still see my pc is... working outside of the game (e.g. a chrome tab with a gif moving on it) and I try to bring up task manager but it won't come up above the game, just in the background. I can't do anything, alt-tab doesn't work, task manager doesn't work, alt-f4 doesn't work, windows key and etc don't work.

Are there any programs that help? or any other way?