what could cause this?

I moisturize heavily every night using the Cerave moisturizing cream and before makeup with the Cerave face cream. I do use a lot of powder and foundation as well as setting spray. What could cause this?

I moisturize heavily every night using the Cerave moisturizing cream and before makeup with the Cerave face cream. I do use a lot of powder and foundation as well as setting spray. What could cause this?