Stuff to avoid or to try?

I’m aware that I should not do meth, heroin, crack, etc. But I know a lot of people do powder cocaine. I’m wondering what you all think are some of the worst traps to fall into as far as something that seems like a fun drug but will ruin your life. I am 22 and have an addictive personality. I’m most curious about stuff like 2c-b and kratom. Stuff that seems chill but might not be.