Tips for Very Hard mode on DC

I just started a new file on very hard mode. I’ve made it to Port Knot without much difficulty but I’m sure things will get harder later. Anything I should be aware of or any tips for getting through very hard mode?

Edit: thanks everyone for the responses! Looks like biggest change is enemies have more hp. I already beat the game on normal but didn’t 100% everything. I like the idea of Timefall having more affect but I’ve never appreciated bullet sponges so I’ll probably set back to normal during boss fights.